Seungeun Oh Ph.D.
I am interested in the post-motitic cell growth of animal cells. Unlike cycling cells which divide when the size is doubled, post-motitic cells may grow many more folds depending on the physiological or developmental need of the tissue. Specifically, in the growth plate of elongating bones, chondrocytes rapidly increase the volume and dry mass as much as 20 fold and these cells undergo three phases of cell growth including a phase of swelling. My aim is to understand the molecular and cellular mechanism of post-mitotic chondrocyte growth and its function in tissue growth. For this, I am developing quantitative microscopy tool to study the dry mass increase of cells in situ.